The ARGONAUT study is seeking volunteers

Do you have a routine colonoscopy scheduled or are you willing to schedule one? You may be eligible to participate in a clinical study investigating colorectal cancer (CRC) treatments and strategies.

Participants may contribute to valuable CRC research. Earn up to $575 or more for your participation.

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why is CRC research and early screening important?

1 in 3

CRC is responsible for 1 in 3 new cancer cases and 12.9% of cancer-related deaths in the United States.

20%

African Americans are 20% more likely to be diagnosed with CRC compared to average rates across other racial and ethnic groups.

what is this study about?

We are seeking to research potential colorectal cancer prevention and treatment strategies through the collection of blood and stool samples from high and low risk populations. Eligible patients will provide samples from the comfort home before and after their next colonoscopy with the assistance of a mobile nurse.

Patients will complete at-home surveys twice a year for eight years to assess long-term changes to symptoms.

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WHO IS THIS STUDY FOR?

Anyone that has scheduled, or is willing to schedule, a routine colonoscopy

Those with or without a personal or family history of colorectal cancer

What do I have to do to participate?

  • Take a short survey here to check if you qualify for the study. If you have a colonoscopy scheduled in the next 30 days, you’ll be immediately taken to a confirmation page to consent and complete your enrollment.
  • A nurse will collect blood and stool samples from you at home before your scheduled colonoscopy.
  • Attend your ONE scheduled colonoscopy.
  • A nurse will collect samples 6 months after your scheduled colonoscopy.
  • Participate in at-home surveys twice a year for eight years (16 total)

You’ll be compensated for your time throughout the study and automatically receive payment for completing tasks. In total you may receive up to $575 or more for completing the study in full.

Sample collection process will repeat only if you have another colonoscopy during the course of the study.

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helpful resources

Frequently Asked Questions

Why should I participate in this study?
By participating in this study, you may contribute to valuable colorectal cancer prevention and treatment research. There is no guaranteed individual benefit from your participation in this study. Information learned from the study may help other people with colorectal cancer and associated treatment.
What should I expect in this study over 8 years?
This is a long-term study. If you are eligible and choose to participate, a nurse will collect blood and stool samples from you at home before your next colonoscopy. Attend your scheduled colonoscopy. A nurse will collect another set of samples 6 months post-colonoscopy. Participate in at-home surveys twice a year for eight years (16 total) and sample collection conditional on future colonoscopies.
When and how will I be compensated?
Participants will be compensated via direct payment after completing certain study activities.
What happens if I am diagnosed with colorectal cancer during the study?
You may still continue in the study with the same participation requirements.
What are the benefits and risks to participation?
Participants are asked to willingly donate stool and blood samples for research that may benefit the cancer community. Participants will be compensated for their time and effort associated with study assessments (samples and surveys).Stool Collection: The use of gloves during stool collection as well as adherence to the instructions provided will minimize any potential exposure to or possible contamination of the stool material that might compromise later analyses. No psychological, cultural, or financial risks are associated with providing stool samples. Blood Collection: Risks associated with having blood drawn are tenderness, pain, bruising, bleeding and/or infection where the needle goes into the skin and blood vein. Participants may also feel nauseated and/or lightheaded for up to 30 minutes after the blood draw. Precautions will be taken to avoid these difficulties.
Who is organizing and funding the research?
Persephone Biosciences is pioneering the use of synthetic biology for microbial products that impact patient and infant health. They are building an end-to-end platform to industrialize the development of engineered cells that restore health to damaged human ecosystems.

A partnership aligned for a cure